Rejuran in Jongno & Myeongdong Rejuran in Seoul, explained.
Rejuran is a polynucleotide (PN) injectable that helps the skin repair itself — improving texture, firmness, fine lines and glow over several weeks rather than adding volume. At Obliv Seoul Origin in Jongno, central Seoul, a physician assesses your skin with Mark-Vu imaging before deciding whether Rejuran suits you.

Rejuran, in brief.
The essentials, answered plainly. Your physician confirms what applies to your skin at consultation.
Ask a physician- What it is
- An injectable "skin healer" made of purified polynucleotides (PN), developed in Korea.
- Best for
- Thin, tired or dehydrated-looking skin, fine lines, enlarged pores, early laxity and post-acne texture.
- How it works
- PN supports the skin's own repair processes and collagen environment, rather than filling or freezing.
- Skin layer treated
- Upper to mid dermis — the layers that govern texture, hydration and quality.
- Treatment time
- About 20–30 minutes, plus numbing cream beforehand.
- Downtime
- Small injection bumps fade within a day; mild redness or pinpoint bruising can last a few days.
- Results
- Gradual — skin quality typically improves over 4–12 weeks after a course.
- Typical course
- Usually 3 sessions, 2–4 weeks apart, then maintenance as advised by your physician.
How does Rejuran work?
Rejuran is made from polynucleotides — DNA fragments purified for medical use. Placed in small amounts across the dermis, they support the skin's natural repair cycle and help create a healthier environment for collagen.
That is why it is described as a skin-quality treatment rather than a filler: it does not change the shape of your face. Instead, skin tends to look denser, smoother and more evenly hydrated as the weeks pass.
In our Skin Architecture approach, Rejuran addresses the upper and mid dermis. If the concern sits deeper — sagging from the fascia, or lost volume — your physician will tell you, and suggest a treatment for that layer instead.
Rejuran or a skin booster — which do I need?
Both improve skin quality, but they do different jobs. Hyaluronic acid boosters mainly hydrate; Rejuran focuses on repair and resilience. Many people with dull, thin skin benefit from Rejuran; those whose main concern is dryness may prefer a hydrating booster — or a combination.
Mark-Vu imaging shows moisture, pores, pigment and wrinkle patterns, so the choice is based on what your skin actually shows rather than what is trending.
What happens on the day?
You meet a physician first. After Mark-Vu imaging and a short consultation, numbing cream is applied for around 30 minutes. The injections themselves take 20–30 minutes.
- Consultation and Mark-Vu imaging with a physician
- Numbing cream applied (around 30 minutes)
- Micro-injections across the treated area (20–30 minutes)
- Soothing care and written aftercare in English
- Your session recorded in the Skin Library for next time
Recovery, aftercare and travel plans
Expect small raised bumps for several hours and possible pinpoint bruising for a few days. Most people return to normal plans the same day; make-up is usually fine from the next day.
Avoid saunas, intense exercise and alcohol for a day or two. If you are visiting Seoul, a session 2–3 days before a flight or an important event is a comfortable margin — tell us your dates on WhatsApp and we will plan around them.
Rejuran is not suitable during pregnancy or breastfeeding, with active skin infection, or with a known allergy to fish-derived products. Your physician will check this at consultation.
Rejuran vs hyaluronic skin booster
| Rejuran (PN) | HA skin booster | |
|---|---|---|
| Main role | Repair and skin resilience | Hydration and plumpness |
| Best for | Thin, tired, textured skin | Dry, dehydrated skin |
| Feel on the day | Small bumps for a few hours | Small bumps for a few hours |
| Results appear | Gradually over weeks | Within days, then settles |
| Typical course | 3 sessions, 2–4 weeks apart | 2–3 sessions, 3–4 weeks apart |
Concerns Rejuran is chosen for
From first message to follow-up.
Consultation, plan and aftercare are handled in English — whether you live in Seoul or are here for a few days.
Message us on WhatsApp with your concerns and travel dates. We reply with availability.
Mark-Vu imaging and a physician consultation identify which skin layer is involved.
A clear plan and pricing before anything begins — often on the same day when appropriate.
Written aftercare, and your records kept in our Skin Library for your next visit.
Not sure it is right for you?
Send a photo and a few lines about your concern. A physician-led team will tell you whether Rejuran suits your skin — or what would suit it better.
Start a WhatsApp enquiry

Rejuran — asked & answered.
General information only. Your physician will advise on what is right for your skin.
Ask your own questionHow many Rejuran sessions do I need?
Most people have a course of 3 sessions, 2–4 weeks apart. Your physician may suggest fewer for maintenance or more for significant texture concerns.
Does Rejuran hurt?
It is a series of fine injections, so there is some stinging. Numbing cream is applied for about 30 minutes beforehand, which most people find makes it very manageable.
When will I see results?
Some people notice a fresher look within one to two weeks. The main improvement in texture and firmness usually builds over 4–12 weeks after a course.
Can I fly after Rejuran?
Yes — flying is not a problem for the treatment itself. We suggest leaving 2–3 days before a flight or event so any bumps or small bruises have settled.
Can Rejuran be combined with lifting or laser?
Often, yes. It is commonly paired with energy-based lifting or laser for a more complete result. Your physician will set the order and spacing so each works well.
Where is the clinic and do you speak English?
We are in Pagoda Tower, 93 Cheonggyecheon-ro, Jongno — about five minutes' walk from Jonggak and Jongno 3-ga stations, and close to Insadong and Myeongdong. Consultations are supported in English, and you can enquire on WhatsApp.
Related treatments.
Rejuran Eye
A finer polynucleotide formula for thin, crepey under-eye skin and fine lines.
Read more → Collagen BoostSkin Booster
Fine injections of hydrating and skin-supporting ingredients for dewy, even skin.
Read more → Collagen BoostJuvelook
PDLLA and hyaluronic acid that encourage collagen — smoother texture, softer fine lines.
Read more → Skin RenewalExosome
Exosome serum applied after resurfacing to help skin settle and recover more comfortably.
Read more → Contour · LiftingUltherapy
Micro-focused ultrasound with live imaging to lift and firm from the SMAS layer.
Read more → Visiting usEnglish-Speaking Skin Clinic
Consultation, consent and aftercare in English, with a concierge on WhatsApp before and after.
Read more →Visit the maison.
Pagoda Tower, 1st–2nd floor
93 Cheonggyecheon-ro, Jongno-gu, Seoul
서울특별시 종로구 청계천로 93 파고다타워 1~2층
Line 2 — Euljiro 1-ga, Euljiro 3-ga
Line 3 — Jongno 3-ga, Euljiro 3-ga
Medical information on this page is for general education and does not replace an in-person consultation. Results, downtime and suitability vary between individuals; all treatments are performed only after physician assessment. Page reviewed by the Obliv Seoul Origin medical team.


